Description
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Details

Background

Creatine kinase M-type is also known as Creatine kinase M chain,M-CK. It is a protein that in humans is encoded by the CKM gene. It belongs to the ATP:guanido phosphotransferase family,containing 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. Creatine kinase M-type can reversibly catalyzes the transfer of phosphate between ATP and various phosphogens. It plays a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability and Storage

Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5.

Synonym

Creatine kinase M-type;Creatine kinase M chain;M-CK;CKM;CKMM

Endotoxin

<1.0 EU per µg as determined by LAL test.

Reconstitution

Please refer to it for detailed information.

Purity

>95% as determined by reducing SDS-PAGE.

Source

Recombinants or rec. proteins

Group

recombinants

Expressed Host

Human cells

Sequence

Met1-Lys381

Mol Mass

44.1 kDa

AP Mol Mass

46 kDa

Accession

P06732

Fusion tag

C-6His

Tissue

muscle

Activity

NA